Research Areas
Fundamental Research on Active Substances of Traditional Chinese Medicine
Fundamental Research on Active Substances of Traditional Chinese Medicine
Education
2003.9-2006.7 Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, PhD
2000.9-2003.7 Henan University of Chinese Medicine, Medicinal Chemistry - Master's Degree
1996.9-2000.7 Henan University of Chinese Medicine, Traditional Chinese Medicine Pharmaceutical Sciences, Bachelor's Degree
Work Experience
2006.8-Present China Academy of Chinese Medical Sciences Institute of Traditional Chinese Medicine
2003.9-2006.7 Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, PhD
2000.9-2003.7 Henan University of Chinese Medicine, Medicinal Chemistry - Master's Degree
1996.9-2000.7 Henan University of Chinese Medicine, Traditional Chinese Medicine Pharmaceutical Sciences, Bachelor's Degree
Work Experience
2006.8-Present China Academy of Chinese Medical Sciences Institute of Traditional Chinese Medicine
Research Project
1: Methodological study on limit detection of aristolochic acid, State Administration of Traditional Chinese Medicine, 2008.1-2009.12
Research on the anti-tumor efficacy, toxic components, and mechanisms of action of traditional Chinese medicine toad venom: National Natural Science Foundation of China 2009.1-2011.12
3: Chemical and Anti-Tumor Activity Studies of Three Toad-Derived Medicinal Materials, Institute-Sponsored Project, 2009.1-2010.12
4, Key Technology Research on Optimal Harvesting Period, Initial Processing, and Storage of Herbs — Lonicera japonica, National 11th Five-Year Support Program, 2006.10-2009
5 Research on multi-indicator evaluation methods and technologies for Chinese medicine quality suited to the characteristics of traditional Chinese medicine; 2007 Special project in the Chinese medicine industry; 2007.7–2009
Comparative study on differences between wild and cultivated medicinal herbs: 6 and 10 types; Ministry of Science and Technology Platform Construction, 2006–2008
7 Research on Quality Control and Evaluation Methods for Traditional Chinese Medicine Compound Formulas: Wuzhuyu Tang, 11th Five-Year Plan Support, 2006–2009
8, Drafting Task for Chinese Pharmacopoeia Standards, National Pharmacopoeia Commission, 2008–2009
9 TCM Production Technology and Process Control Standards Platform, "Major New Drug Development" Special Project, 2008–2010
10 Comprehensive New Chinese Medicine R&D Technology Platform – CMC Platform, "Major New Drug Creation" Special Program, 2008–2010
1: Methodological study on limit detection of aristolochic acid, State Administration of Traditional Chinese Medicine, 2008.1-2009.12
Research on the anti-tumor efficacy, toxic components, and mechanisms of action of traditional Chinese medicine toad venom: National Natural Science Foundation of China 2009.1-2011.12
3: Chemical and Anti-Tumor Activity Studies of Three Toad-Derived Medicinal Materials, Institute-Sponsored Project, 2009.1-2010.12
4, Key Technology Research on Optimal Harvesting Period, Initial Processing, and Storage of Herbs — Lonicera japonica, National 11th Five-Year Support Program, 2006.10-2009
5 Research on multi-indicator evaluation methods and technologies for Chinese medicine quality suited to the characteristics of traditional Chinese medicine; 2007 Special project in the Chinese medicine industry; 2007.7–2009
Comparative study on differences between wild and cultivated medicinal herbs: 6 and 10 types; Ministry of Science and Technology Platform Construction, 2006–2008
7 Research on Quality Control and Evaluation Methods for Traditional Chinese Medicine Compound Formulas: Wuzhuyu Tang, 11th Five-Year Plan Support, 2006–2009
8, Drafting Task for Chinese Pharmacopoeia Standards, National Pharmacopoeia Commission, 2008–2009
9 TCM Production Technology and Process Control Standards Platform, "Major New Drug Development" Special Project, 2008–2010
10 Comprehensive New Chinese Medicine R&D Technology Platform – CMC Platform, "Major New Drug Creation" Special Program, 2008–2010
Published Papers (2004-Present)
1 Huimin Gao, Zhimin Wang, Weihao Wang. A new triterpenoid saponin from the stem of Akebia trifoliata var. australis. J. Asian Nat. Prod. Res. 2009, accepted.
2 Huimin Gao, Jinxiu Liu, Zhimin Wang*, Weihao Wang. Phytolacacinoside A, a new triterpenoid saponin from *Phytolacca acinosa* Roxb. J. Asian Nat. Prod. Res. 2009, 11(5): 433-438.
3, Huimin Gao, Zhimin Wang. Triterpenoid saponins and phenylethanoid glycosides from the stem of Akebia trifoliata var. australis. Phytochemistry 2006, 67: 2697-2705.
4, Limei Lin, Xiaoguang Zhang, Jingjing Zhu, Huimin Gao, Zhimin Wang, and Weihao Wang. Two new triterpenoid saponins from the flowers and buds of Lonicera japonica. J. Asian Nat. Prod. Res. 2008, 10(10): 925-929.
5, Gao Huimin, Wang Zhimin, Fu Xue Tao, Wang Weihao, Wang Guan. Determination of Saponin Components in Aristolochia Manshuriensis Herb by RP-HPLC. Chinese Pharmaceutical Journal. 2007, 42(1): 20-23.
6 Gao Huimin, Wang Zhimin, Qu Li, Fu Xue Tao, Li Lin. Determination of Acteoside in Akebia Caulis by RP-HPLC. Chinese Journal of Traditional Chinese Medicine. 2007, 32(6): 476-478.
7, Gao Huimin, Wang Zhimin. A new triterpenoid saponin from Akebia quinata [J]. Acta Pharmaceutica Sinica. 2006, 41(9): 835-839.
8, Gao Huimin, Wang Zhimin, Wang Jiaming. Study on Chemical Constituents of Actinidia polygama (I). Chinese Journal of Pharmacy. 2006,41(5):333-335.
9, Gaohuimin, Wang Zhimin. Study on chemical constituents of Akebia trifoliata (II). Chinese Journal of Pharmacy. 2006,41(6):418-420.
10, Gaohuimin, Wangzhimin. Research progress on medicinal plants of the genus Akebia. Chinese Journal of Chinese Materia Medica. 2006,31(1):10-14.
11, Gao Huimin, Wang Zhimin, Tian Juan. Pharmacokinetics and metabolite study of breviscapine in normal and model rats. Acta Pharmaceutica Sinica. 2005,40 (11): 1024-1027.
12, Gao Huimin, Wang Zhimin, Wang Jinhua, Xue Baoyun, Li Wen. Effects of Zizyphus jujuba polysaccharide on hemorheological parameters in rats with thrombosis induced by carrageenan. Chinese Journal of Experimental Traditional Medical Formulae. 2005,11(6): 45-47.
13 Xiong Yan, Gao Huimin, Wang Zhimin, Zhu Jingjing. Study on HPLC Fingerprint of Different Drying Technologies for Lonicera japonica. Chinese Journal of Traditional Chinese Medicine 2009, 8: 1015-1017.
14, Wang Zhi-min, Gao Hui-min, Fu Xue-tao, Wang Wei-hao. Methodological study on the quality evaluation of Chinese medicine based on the "one test multiple evaluations" method. China Journal of Chinese Materia Medica.2006,31(23):1925-1928.
15, Dai Liping, Gao Huimin, Wang Zhimin, and Wang Weihao. Separation and structural identification of chemical constituents from toad skin. Acta Pharmaceutica Sinica. 2007, 42(8): 858-861.
16, Wang Jiaming, Gao Huimin, Hong Yumei, and Wang Zhimin. HPLC Analysis of α-Hederagenin in Pre-knowledge Substances. Chinese Journal of Pharmacy. 2006, 41(16): 1212-1213.
17, Wang Jiaming, Gao Huimin, Wang Zhimin, Wang Weihao. HPLC analysis of saponins PK in Pseudostellariae Radix. Chinese Journal of Pharmaceutical Sciences. 2007, 42(12): 896-898.
18, Li Lin, Gao Huimin, Wang Zhimin, Wang Weihao. Content of aristolochic acid A in Guanxin Suhe preparation. Chinese Journal of Traditional Chinese Medicine.2006,31(2): 122-124.
19, Ge Yuewei, Gao Huimin, Wang Zhimin. Research progress on Curcuma plants. Chinese Journal of Traditional Chinese Medicine. 2007, 32(23): 2461-2467.
20, Ge Yuewei, Gao Huimin, Wang Weihao, and Wang Zhimin. Study on Chemical Constituents of Curcumae Phaeocaulis I. Chinese Journal of Pharmacy. 2007,42(11): 822-824.
1 Huimin Gao, Zhimin Wang, Weihao Wang. A new triterpenoid saponin from the stem of Akebia trifoliata var. australis. J. Asian Nat. Prod. Res. 2009, accepted.
2 Huimin Gao, Jinxiu Liu, Zhimin Wang*, Weihao Wang. Phytolacacinoside A, a new triterpenoid saponin from *Phytolacca acinosa* Roxb. J. Asian Nat. Prod. Res. 2009, 11(5): 433-438.
3, Huimin Gao, Zhimin Wang. Triterpenoid saponins and phenylethanoid glycosides from the stem of Akebia trifoliata var. australis. Phytochemistry 2006, 67: 2697-2705.
4, Limei Lin, Xiaoguang Zhang, Jingjing Zhu, Huimin Gao, Zhimin Wang, and Weihao Wang. Two new triterpenoid saponins from the flowers and buds of Lonicera japonica. J. Asian Nat. Prod. Res. 2008, 10(10): 925-929.
5, Gao Huimin, Wang Zhimin, Fu Xue Tao, Wang Weihao, Wang Guan. Determination of Saponin Components in Aristolochia Manshuriensis Herb by RP-HPLC. Chinese Pharmaceutical Journal. 2007, 42(1): 20-23.
6 Gao Huimin, Wang Zhimin, Qu Li, Fu Xue Tao, Li Lin. Determination of Acteoside in Akebia Caulis by RP-HPLC. Chinese Journal of Traditional Chinese Medicine. 2007, 32(6): 476-478.
7, Gao Huimin, Wang Zhimin. A new triterpenoid saponin from Akebia quinata [J]. Acta Pharmaceutica Sinica. 2006, 41(9): 835-839.
8, Gao Huimin, Wang Zhimin, Wang Jiaming. Study on Chemical Constituents of Actinidia polygama (I). Chinese Journal of Pharmacy. 2006,41(5):333-335.
9, Gaohuimin, Wang Zhimin. Study on chemical constituents of Akebia trifoliata (II). Chinese Journal of Pharmacy. 2006,41(6):418-420.
10, Gaohuimin, Wangzhimin. Research progress on medicinal plants of the genus Akebia. Chinese Journal of Chinese Materia Medica. 2006,31(1):10-14.
11, Gao Huimin, Wang Zhimin, Tian Juan. Pharmacokinetics and metabolite study of breviscapine in normal and model rats. Acta Pharmaceutica Sinica. 2005,40 (11): 1024-1027.
12, Gao Huimin, Wang Zhimin, Wang Jinhua, Xue Baoyun, Li Wen. Effects of Zizyphus jujuba polysaccharide on hemorheological parameters in rats with thrombosis induced by carrageenan. Chinese Journal of Experimental Traditional Medical Formulae. 2005,11(6): 45-47.
13 Xiong Yan, Gao Huimin, Wang Zhimin, Zhu Jingjing. Study on HPLC Fingerprint of Different Drying Technologies for Lonicera japonica. Chinese Journal of Traditional Chinese Medicine 2009, 8: 1015-1017.
14, Wang Zhi-min, Gao Hui-min, Fu Xue-tao, Wang Wei-hao. Methodological study on the quality evaluation of Chinese medicine based on the "one test multiple evaluations" method. China Journal of Chinese Materia Medica.2006,31(23):1925-1928.
15, Dai Liping, Gao Huimin, Wang Zhimin, and Wang Weihao. Separation and structural identification of chemical constituents from toad skin. Acta Pharmaceutica Sinica. 2007, 42(8): 858-861.
16, Wang Jiaming, Gao Huimin, Hong Yumei, and Wang Zhimin. HPLC Analysis of α-Hederagenin in Pre-knowledge Substances. Chinese Journal of Pharmacy. 2006, 41(16): 1212-1213.
17, Wang Jiaming, Gao Huimin, Wang Zhimin, Wang Weihao. HPLC analysis of saponins PK in Pseudostellariae Radix. Chinese Journal of Pharmaceutical Sciences. 2007, 42(12): 896-898.
18, Li Lin, Gao Huimin, Wang Zhimin, Wang Weihao. Content of aristolochic acid A in Guanxin Suhe preparation. Chinese Journal of Traditional Chinese Medicine.2006,31(2): 122-124.
19, Ge Yuewei, Gao Huimin, Wang Zhimin. Research progress on Curcuma plants. Chinese Journal of Traditional Chinese Medicine. 2007, 32(23): 2461-2467.
20, Ge Yuewei, Gao Huimin, Wang Weihao, and Wang Zhimin. Study on Chemical Constituents of Curcumae Phaeocaulis I. Chinese Journal of Pharmacy. 2007,42(11): 822-824.
Patent
1: Application of bonded silica-based composite materials for heavy metal removal from Chinese medicine extracts, Application No. 200710178048.1
2: Elsholtzia ciliata extract and its medical use, Application No. 200710176662.4
3. A method for removing aristolochic acid from Chinese herbal medicine and its limit standard, Application No. 200710064392.8
1: Application of bonded silica-based composite materials for heavy metal removal from Chinese medicine extracts, Application No. 200710178048.1
2: Elsholtzia ciliata extract and its medical use, Application No. 200710176662.4
3. A method for removing aristolochic acid from Chinese herbal medicine and its limit standard, Application No. 200710064392.8
Results
1: Standardization research on the processing of traditional Chinese medicines containing aristolochic acid. 2007: First Prize for Technological Progress, China Association of Traditional Chinese Medicine (ranked 3rd).
2. Chemical and quality evaluation study of Akebia caulis and Pseudofructus Gleditsiae. Ranked 2nd for the Third-Class Science and Technology Progress Award of China Academy of Chinese Medical Sciences in 2007.
3. Investigation of Akebia resources and quality evaluation research, Third Prize in Science and Technology awarded by the Chinese Pharmaceutical Association in 2008, ranked fourth.
4. Standardized demonstration study on Chinese herbal processing auxiliaries vinegar and wine, Second Prize in Science and Technology Progress of China Academy of Chinese Medical Sciences in 2008 year. Ranked 7th.
1: Standardization research on the processing of traditional Chinese medicines containing aristolochic acid. 2007: First Prize for Technological Progress, China Association of Traditional Chinese Medicine (ranked 3rd).
2. Chemical and quality evaluation study of Akebia caulis and Pseudofructus Gleditsiae. Ranked 2nd for the Third-Class Science and Technology Progress Award of China Academy of Chinese Medical Sciences in 2007.
3. Investigation of Akebia resources and quality evaluation research, Third Prize in Science and Technology awarded by the Chinese Pharmaceutical Association in 2008, ranked fourth.
4. Standardized demonstration study on Chinese herbal processing auxiliaries vinegar and wine, Second Prize in Science and Technology Progress of China Academy of Chinese Medical Sciences in 2008 year. Ranked 7th.