Research Areas
Chemistry of Traditional Chinese Medicine and Development of New TCM Drugs
Chemistry of Traditional Chinese Medicine and Development of New TCM Drugs
Education
1986 Beijing School of Traditional Chinese Medicine
1993 Bachelor's degree from Beijing University of Chinese Medicine
Master of Traditional Chinese Medicine, University of Macau (202007)
1997 Senior Technician
2000 National Licensed Pharmacist Qualification
2008 Associate Researcher
1986 Beijing School of Traditional Chinese Medicine
1993 Bachelor's degree from Beijing University of Chinese Medicine
Master of Traditional Chinese Medicine, University of Macau (202007)
1997 Senior Technician
2000 National Licensed Pharmacist Qualification
2008 Associate Researcher
Work Experience
1986–Present, Chemistry Division, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences
2002–8: 3-month research fellowship at the Department of Pharmaceutical Resources, Shizuoka Prefectural University of Pharmacy, Japan
1986–Present, Chemistry Division, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences
2002–8: 3-month research fellowship at the Department of Pharmaceutical Resources, Shizuoka Prefectural University of Pharmacy, Japan
Research Project
I. Hosted Projects
1. Development and research on Lotus Plumule Total Alkaloids for treating myocardial ischemia, a project of the National Administration of Traditional Chinese Medicine.
2. Study on Quality Standards for Toxic Components of Traditional Chinese Medicine Senecio scandens and Its Preparations, a project of the National Administration of Traditional Chinese Medicine
3. Comparative Study of Reference Standards for Ten Chinese Medicinal Herbs Including Caulis Cynanchi Atrati — Leader of the Cynanchum Bungei Sub-Project, Ministry of Science and Technology Research Project
4. Medicinal materials and processed pieces of *Spatholobi Caulis*: National Pharmacopoeia Commission project
II. Key Participating Projects
1. Development and research on the lyophilized powder injection of National Class 1 New Drug ACT for treating chronic glomerulonephritis, Ministry of Science and Technology project
2. Research on Quality Standards of Traditional Chinese Medicine Materials – Plantago Herb, Ministry of Science and Technology Project
3. Research on cultivation standards for common Chinese medicinal herbs such as ginseng and Panax notoginseng, Ministry of Science and Technology project
4. Research on Quality Standards for Ardisia Crenata Decoction Pieces, Ministry of Science and Technology Project
5. Ministry of Science and Technology project on research models for new drugs treating atherosclerosis and development of Class V drug Canlian Tablets
6. Research on Medicinal Standards for Processing Aids of Dual-Purpose Black Bean Juice: Ministry of Science and Technology Project
7. Safety Evaluation Research on Traditional Chinese Medicine Injections, Ministry of Science and Technology Project
8. Research on Bacterial Endotoxin Detection Methods for Traditional Chinese Medicine Injectables, Ministry of Science and Technology Project
9. Development of Traditional Chinese Medicine BLG for Avian Influenza Treatment, Macau Science and Technology Development Fund Project
Published Papers (2004-Present)
1. Comparison of 3 active ingredients in fresh, dried, and processed Rehmannia roots by Wang Hongjie, Jin Yahong, Li Pengyue, Li Lihua, and Bian Baolin. China Journal of Chinese Materia Medica, 2008.33(15): 50
2. Wang Hongjie, Liu Ting, Liang Aihua, and Bian Baolin. Isolation, Identification, and Preliminary Study of Bioactive Compounds from Fresh Rehmannia Root. Chinese Journal of Experimental Traditional Medical Formulae, 2007.13(1): 15.
3. Wang Hongjie, Si Nan, and Bian Baolin. Determination of Cynanchum paniculatum glycoside A content in Cynanchum paniculatum. Chinese Journal of Experimental Traditional Medical Formulae, 2005.11(1): 5.
4. Wang Hongjie, Si Nan, Bian Baolin. Comparative Study on the Dissolution of Main Effective Components in Decoction Pieces Before and After Ultrafine Grinding. Chinese Journal of Traditional Chinese Medicine, 2004.29(11): 1111
5. Fan Miao-xuan, Wang Hong-jie, Li Xiao-ming, Bian Bao-lin. Study on chemical constituents of Xiaochengqi Tang and analysis of volatile oil components. Chinese Journal of Traditional Chinese Medicine, 2008.33(9): 1027
6. Li Yanyan, Wang Hongjie, Yang Jian, and Bian Baolin. Study on the purification process of water-soluble active components from Pueraria lobata and Salvia miltiorrhiza using macroporous resin. Chinese Journal of Experimental Traditional Medical Formulae 2008.14(1): 20.
7. Liu Wei, Wang Hongjie, Si Nan, and Bian Baolin. Preparation process and content determination of total alkaloids from Nelumbo nucifera plumule in drops: China Journal of Chinese Materia Medica, 2007.32(7): 581.
8. Liu Wei, Wang Hongjie, and Bian Baolin. Study on the purification process of total alkaloids from lotus plumule by macroporous adsorption resin. Chinese Journal of Experimental Traditional Medical Formulae, 2007.13(3): 23.
9. He Xirong, Wang Hongjie. Morphological identification of Senecio scandens and Aster simplex. Chinese Journal of Experimental Traditional Medical Formulae, 2006, 12(7): 15
10. Bian Baolin, Wang Hongjie, Si Nan, Yang Jian, and Bai Wei chemical component research, Chinese Herbal Medicines, 2005.36(7): 990
11. Si Nan, Wang Hongjie, Bian Baolin. Comparison of six-ingredient Rehmannia decoction pieces, micro-fine water extracts under different grinding conditions, and paeonol content. Chinese Journal of Experimental Traditional Medical Formulae, 2005.11(6): 28.
12. Bian Baolin, Wang Hongjie, Si Nan. Determination of Epicatechin Content in the Herb Caesalpinia Sappan L., Chinese Journal of Experimental Traditional Medical Formulae, 2004.6(10):31
13. Li Yanyan, Bian Baolin, Yang Jian, Wang Hongjie. Study on the molding process of Gegen Danshen Capsules. Chinese Journal of Experimental Traditional Medical Formulae, 2008, 14(1): 20
14. Yang Qing, Nie Shuqin, Weng Xiaogang, Wang Hongjie, He Xirong, and Huang Luqi. Comparative study on the pharmacodynamic effects of Aconite Lateral Root (prepared) combined with different varieties of Fritillaria. Chinese Journal of Experimental Traditional Medical Formulae, 2006, 12(6): 25.
15. Bian Bao Lin, Si Nan, Wang Hongjie, Yang Jian, He Xirong. Study on the changes in content of toxic components such as aconitine, mesaconitine, and neoaconitine after decocting Fuzi alone or with Fritillaria: China Journal of Experimental Traditional Medical Formulae, 2006.12(4)
1. Comparison of 3 active ingredients in fresh, dried, and processed Rehmannia roots by Wang Hongjie, Jin Yahong, Li Pengyue, Li Lihua, and Bian Baolin. China Journal of Chinese Materia Medica, 2008.33(15): 50
2. Wang Hongjie, Liu Ting, Liang Aihua, and Bian Baolin. Isolation, Identification, and Preliminary Study of Bioactive Compounds from Fresh Rehmannia Root. Chinese Journal of Experimental Traditional Medical Formulae, 2007.13(1): 15.
3. Wang Hongjie, Si Nan, and Bian Baolin. Determination of Cynanchum paniculatum glycoside A content in Cynanchum paniculatum. Chinese Journal of Experimental Traditional Medical Formulae, 2005.11(1): 5.
4. Wang Hongjie, Si Nan, Bian Baolin. Comparative Study on the Dissolution of Main Effective Components in Decoction Pieces Before and After Ultrafine Grinding. Chinese Journal of Traditional Chinese Medicine, 2004.29(11): 1111
5. Fan Miao-xuan, Wang Hong-jie, Li Xiao-ming, Bian Bao-lin. Study on chemical constituents of Xiaochengqi Tang and analysis of volatile oil components. Chinese Journal of Traditional Chinese Medicine, 2008.33(9): 1027
6. Li Yanyan, Wang Hongjie, Yang Jian, and Bian Baolin. Study on the purification process of water-soluble active components from Pueraria lobata and Salvia miltiorrhiza using macroporous resin. Chinese Journal of Experimental Traditional Medical Formulae 2008.14(1): 20.
7. Liu Wei, Wang Hongjie, Si Nan, and Bian Baolin. Preparation process and content determination of total alkaloids from Nelumbo nucifera plumule in drops: China Journal of Chinese Materia Medica, 2007.32(7): 581.
8. Liu Wei, Wang Hongjie, and Bian Baolin. Study on the purification process of total alkaloids from lotus plumule by macroporous adsorption resin. Chinese Journal of Experimental Traditional Medical Formulae, 2007.13(3): 23.
9. He Xirong, Wang Hongjie. Morphological identification of Senecio scandens and Aster simplex. Chinese Journal of Experimental Traditional Medical Formulae, 2006, 12(7): 15
10. Bian Baolin, Wang Hongjie, Si Nan, Yang Jian, and Bai Wei chemical component research, Chinese Herbal Medicines, 2005.36(7): 990
11. Si Nan, Wang Hongjie, Bian Baolin. Comparison of six-ingredient Rehmannia decoction pieces, micro-fine water extracts under different grinding conditions, and paeonol content. Chinese Journal of Experimental Traditional Medical Formulae, 2005.11(6): 28.
12. Bian Baolin, Wang Hongjie, Si Nan. Determination of Epicatechin Content in the Herb Caesalpinia Sappan L., Chinese Journal of Experimental Traditional Medical Formulae, 2004.6(10):31
13. Li Yanyan, Bian Baolin, Yang Jian, Wang Hongjie. Study on the molding process of Gegen Danshen Capsules. Chinese Journal of Experimental Traditional Medical Formulae, 2008, 14(1): 20
14. Yang Qing, Nie Shuqin, Weng Xiaogang, Wang Hongjie, He Xirong, and Huang Luqi. Comparative study on the pharmacodynamic effects of Aconite Lateral Root (prepared) combined with different varieties of Fritillaria. Chinese Journal of Experimental Traditional Medical Formulae, 2006, 12(6): 25.
15. Bian Bao Lin, Si Nan, Wang Hongjie, Yang Jian, He Xirong. Study on the changes in content of toxic components such as aconitine, mesaconitine, and neoaconitine after decocting Fuzi alone or with Fritillaria: China Journal of Experimental Traditional Medical Formulae, 2006.12(4)
Patent
1 Invention Patents: 1
Total triterpenoid saponins from Ardisia crenata and related species and preparation method thereof (2003)
Monograph
Research on Quality Standards of Chinese Herbal Medicines (2006) Participants
Research on Quality Standards of Chinese Herbal Medicines (2006) Participants
Results
National Science and Technology Progress Award: One
Research on Quality Standards and Reference Materials of 66 Common Chinese Medicinal Herbs (2001) — Second Prize, Participant
Beijing Science and Technology Award: 2 awards
Research on Active Ingredients of Rehmannia Leaves for Treating Glomerulonephritis (2004) Third Prize, Second Place
Study on the Anti-tumor Activity of Pentacyclic Triterpene Saponins from Ardisia Crenata (2006 Year) — Third Prize, Fourth Place
China Association of Chinese Medicine Science and Technology Award: One
Study on Active Components in Rehmannia Leaves for Treating Chronic Glomerulonephritis (2004) — Third Prize, Second Place
Chinese Academy of Traditional Chinese Medicine Awards: 4
Study on Active Components in Rehmannia Leaves for Treating Glomerulonephritis (2003) Second Prize, Second Place
Research on Anti-Tumor Active Components of Ardisia crenata (2002) – Second Prize, 4th Place
Quality Standard Research on Traditional Chinese Medicines (including Rhubarb, Hawthorn, Salvia Miltiorrhiza, etc., 13 types) (2004) — Second Prize, Participant
Research on Technical Standards for Safety Limits of Heavy Metals and Pesticide Residues in Eight Traditional Chinese Medicines, Including Rehmannia and Notoginseng – Third Prize
China Association of Chinese Medicine Outstanding Paper Award: One
Comparison of 3 Active Ingredients in Fresh, Raw, and Processed Rehmannia Root (Year 2007)
New Drug Certificate: 2 items
Total Glucosides of Rehmannia Capsules (2007) National Drug Certificate No. Z20070013
Total Glucosides of Paeony ( 2007 ) Drug Approval No. Z20070011
National Science and Technology Progress Award: One
Research on Quality Standards and Reference Materials of 66 Common Chinese Medicinal Herbs (2001) — Second Prize, Participant
Beijing Science and Technology Award: 2 awards
Research on Active Ingredients of Rehmannia Leaves for Treating Glomerulonephritis (2004) Third Prize, Second Place
Study on the Anti-tumor Activity of Pentacyclic Triterpene Saponins from Ardisia Crenata (2006 Year) — Third Prize, Fourth Place
China Association of Chinese Medicine Science and Technology Award: One
Study on Active Components in Rehmannia Leaves for Treating Chronic Glomerulonephritis (2004) — Third Prize, Second Place
Chinese Academy of Traditional Chinese Medicine Awards: 4
Study on Active Components in Rehmannia Leaves for Treating Glomerulonephritis (2003) Second Prize, Second Place
Research on Anti-Tumor Active Components of Ardisia crenata (2002) – Second Prize, 4th Place
Quality Standard Research on Traditional Chinese Medicines (including Rhubarb, Hawthorn, Salvia Miltiorrhiza, etc., 13 types) (2004) — Second Prize, Participant
Research on Technical Standards for Safety Limits of Heavy Metals and Pesticide Residues in Eight Traditional Chinese Medicines, Including Rehmannia and Notoginseng – Third Prize
China Association of Chinese Medicine Outstanding Paper Award: One
Comparison of 3 Active Ingredients in Fresh, Raw, and Processed Rehmannia Root (Year 2007)
New Drug Certificate: 2 items
Total Glucosides of Rehmannia Capsules (2007) National Drug Certificate No. Z20070013
Total Glucosides of Paeony ( 2007 ) Drug Approval No. Z20070011